Shahid Beheshti
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Personal Information            

Name                                          Seyed Amir

Surname                                     Jalali

Date of birth                               July 03, 1981

Place of birth                              Tehran, Iran

Sex                                              Male

Nationality                                  Iranian

E-mail                                         Jalalia@sbmu.ac.ir,  Jalali5139@yahoo.com

     Assistant Professor in Immunology, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Mailing Address: School of Medicine, Koodakyar St. Danshjoo Blv, Velenjak, Shahid Chamran Highway, Tehran, Iran

Postal Code:1985717443

Fax: + 98 21- 224 399 70

 Phone: +98 21-238 725 45

 

 

 

   

Educations:

  1.  B.Sc. in Medical Laboratory Sciences, Tehran University of Medical Science, Tehran, Iran, 1999-2003
  2. M.Sc. in Immunology, Shiraz University of Medical
  3. Sciences, Shiraz, Iran, 2003-2006
  4. Ph.D. in Immunology, Mashhad University of Medical
  5. Sciences, Mashhad, Iran, 2006-2011
  6. Research fellowship, cancer vaccine and immunotherapy. San Raffaele hospital, Milan, Italy.  2010-2011

 

Professional experiences:

Research experiences:

  1. •  Cancer vaccine development
  2. •  Cancer genetics and immuno-genetics
  3. •  Leishmania vaccine development
  4. •  Nanocarriers  Liposom

Technical experiences:

  1. •  Immunological assays, including isolation of spleen/lymph node cells from experimental animals, proliferation, cytotoxicity and cytokine assays (Flow cytometry, ELISA and ELISpot).
  2. •  Cell culture methods
  3. •  Different methods of DNA and RNA extraction, cDNA synthesis
  4. •  Developing PCR, RT-PCR, restriction enzyme usage and Gel electrophoresis
  5. •  Immunochemistry techniques including IHC, SDS-PAGE.
  6. •  Preparation and characterization of nanoparticles like liposome

 

Publications:

Articles:

  1. •  Amirghofran Z, Jalali SA, Ghaderi A, Hosseini SV. Genetic polymorphism in the transforming growth factor beta1 gene (-509 C/T and -800 G/A) and colorectal cancer. Cancer Genet Cytogenet. 2009 Apr 1;190(1):21-5
  2. •  Amirghofran Z, Jalali SA, Hosseini SV, Vasei M, Sabayan B, Ghaderi A. Evaluation of CD44 and CD44v6 in colorectal carcinoma patients: soluble forms in relation to tumor tissue expression and metastasis. J Gastrointest Cancer. 2008;39(1-4):73-8.
  3. •  Jalali SA, Parmiani G. Pre-clinical and clinical aspects of peptide-based vaccine against human solid tumors. Recent Pat Biotechnol. 2011 Jun 27: 108-117.
  4. •  Seyed Amir Jalali, Mojtaba Sankian, Jalil Tavakkol-Afshari, Mahmoud Reza Jaafari. Induction of Tumor-Specific Immunity By Multi-epitope Rat HER2/neu-derived peptides encapsulated in LPD nanoparticles. Nanomedicine. 2012 Jul;8(5):692-701
  5. •  Heravi Shargh V, Jaafari MR, Khamesipour A, Jalali SA, Firouzmand H, Abbasi A, Badiee A. Cationic liposomes containing soluble Leishmania antigens (SLA) plus CpG ODNs induce protection against murine model of leishmaniasis. Parasitol Res. 2012 Jul;111(1):105-14.
  6. •  Shargh VH, Jaafari MR, Khamesipour A, Jaafari I, Jalali SA, Abbasi A, Badiee A. Liposomal SLA co-incorporated with PO CpG ODNs or PS CpG ODNs induce the same protection against the murine model of leishmaniasis. Vaccine. 2012 Jun 6;30(26):3957-64
  7. •  Alavizadeh SH, Badiee A, Khamesipour A, Jalali SA, Firouzmand H, Abbasi A, Jaafari MR. The role of liposome-protamine-DNA nanoparticles containing CpG oligodeoxynucleotides in the course of infection induced by Leishmania major in BALB/c mice. Exp Parasitol. 2012 Nov;132(3):313-9
  8. •  Chavoshian O, Biari N, Badiee A, Khamesipour A, Abbasi A, Saberi Z, Jalali SA, Jaafari MR. Sphingomyelin Liposomes Containing Soluble Leishmania major antigens Induced Strong Th2 Immune Response in BALB/c Mice. Iran J Basic Med Sci. 2013 Sep;16(9):965-72.
  9. •  Ghorbani A, Jalali SA, Varedi M. Isolation of adipose tissue mesenchymal stem cells without tissue destruction: A non-enzymatic method. Tissue Cell. 2013 Nov 12.
  10. •  Kaveh Shahveisi , Seyed Hadi Mousavi, Mahmoud Hosseini , Abolfazl Khajavi Rad, Seyed Amir Jalali, Ziba Rajaei, Hamid Reza Sadeghnia , Mousa-Al-Reza Hadjzadeh. The role of local renin-angiotensin system on high glucose-induced cell toxicity, apoptosis and reactive oxygen species production in PC12 cells. Iran J Basic Med Sci. 2014 Agu; 17(8)
  11. •  Mansourian M, Badiee A, Jalali SA, Shariat S, Yazdani M, Amin M, Jaafari MR. Effective induction of anti-tumor immunity using p5 HER-2/neu derived peptide encapsulated in fusogenic DOTAP cationic liposomes co-administrated with CpG-ODN. Immunol Lett. 2014 Jul 30. pii: S0165-2478(14)00148-5. doi: 10.1016/j.imlet.2014.07.008.
  12. •  Shariat S, Badiee A, Jalali SA, Mansourian M, Yazdani M, Mortazavi SA, Jaafari MR. P5 HER2/neu-derived peptide conjugated to liposomes containing MPL adjuvant as an effective prophylactic vaccine formulation for breast cancer. Cancer Lett. 2014 Sep 16. pii: S0304-3835(14)00528-X. doi: 10.1016/j.canlet.2014.09.016.

 

Book:

•  Laboratory diagnosis of infectious diseases. Shiraz: Nemati Publishing, 2006 (Persian)

 

 

 

 

 

Shahid Beheshti university of Medical Sciences

t Iran, Tehran
Velenjak St. , Shahid Chamran Highway
Tel : +98 21 22 43 99 82
Fax : +98 21 22 43 97 84
Email : intl_office@sbmu.ac.ir

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